24-Nor Ursodeoxycholic Acid-d5

• 产品号: N865302
• 分子式: C23H38O4
• 分子量: 378.54542

产品别名

• 标题: 24-Nor Ursodeoxycholic Acid-d5
• IUPAC标准名: (3R)-3-[(1S,2S,5R,7R,9S,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]butanoic acid
• IUPAC传统名: (3R)-3-[(1S,2S,5R,7R,9S,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]butanoic acid
• 别名: 3α,7β-Dihydroxy-24-nor-5β-cholan-23-oic Acid-d5; (3α,5β,7β)-3,7-Dihydroxy-24-norcholan-23-oic Acid-d5; Norursodeoxycholic Acid-d5

产品详细信息

详细说明 (English)

Labelled Ursodeoxycholic Acid (U850000) derivative. 24-norUrsodeoxycholic acid is superior to Ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.

参考文献

• Seedorf, U., et al.: J. Biol. Chem., 269, 21277 (1994)
• Stolowich, N., et al.: Biochemistry, 36, 1719 (1994)