NO-Aspirin 1

• 产品号: N633000
• CAS号: 175033-36-0
• 分子式: C16H13NO7
• 分子量: 331.27692
• 保 存: -20°C Freezer

产品别名

• 标题: NO-Aspirin 1
• IUPAC标准名: 3-[(nitrooxy)methyl]phenyl 2-(acetyloxy)benzoate
• IUPAC传统名: 3-[(nitrooxy)methyl]phenyl 2-(acetyloxy)benzoate
• 别名: 3-(Nitroxymethyl)phenyl 2-acetoxybenzoate; NCX 4016; 2-Acetyloxybenzoic Acid 3-Nitrooxymethylphenyl Ester

产品登记号

• CAS号: 175033-36-0

产品性质

• 外观: Off-White Solid
• 熔点: 61-62°C
• 溶解度: Acetonitrile
• 溶解度: Chloroform
• 溶解度: Dichloromethane
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

NO-Aspirin 1 is a hybrid molecule of aspirin and a nitric oxide (NO) donor. It contains an ester linkage, that when cleaved by esterases in the gut, liver, and plasma releases salicylate and an NO-releasing moiety. It also prevents restinosiis, inhibit

参考文献

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• Takeuchi, K, et al.: J. Physiol. Pharmacol., 49, 501 (1997)
• Bak, A.W., et al.: Life Sci., 62, 367 (1997)
• Wallace, J.L., et al.: Nature Reviews Drug Discovery, 1, 375 (1997)
• Chiroli, V., et a