β-Nicotinamide Mononucleotide

• 产品号: N407765
• CAS号: 1094-61-7
• 分子式: C11H15N2O8P
• 分子量: 334.219161

产品别名

• 标题: β-Nicotinamide Mononucleotide
• IUPAC标准名: 3-carbamoyl-1-[(2R,4R,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1λ^5-pyridin-1-ylium
• IUPAC传统名: 3-carbamoyl-1-[(2R,4R,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1λ^5-pyridin-1-ylium
• 别名: NMN; Nicotinamide Ribotide; Nicotinamide Mononucleotide; β-D-NMN; Nicotinamide Ribonucleoside 5'-Phosphate; 3-(Aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium Inner Salt; 3-Carbamoyl-1-β-D-ribofuranosylpyridinium Hydroxide, 5'-Phosphate Inner Salt; Nicotinamide Ribonucleotide; β-NMN

产品登记号

• CAS号: 1094-61-7

产品详细信息

详细说明 (English)

A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and rest

参考文献

• Yoshino, J. et al.: Cell Metab., 14, 528 (2011)
• Caton, P.W. et al.: Diabetologia, 54, 3083 (2011)
• Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2011)