Nevirapine-d5See N391278

• 产品号: N391277
• 分子式: C15H14N4O
• 分子量: 266.29786
• 保 存: -20°C Freezer

产品别名

• 标题: Nevirapine-d5See N391278
• IUPAC标准名: 2-(^2H₅)cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one
• IUPAC传统名: 2-(^2H₅)cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one
• 别名: Viramune-d5; Nevarapine-d5; BI-RG 587-d5; 11-(Cyclopropyl-d5)-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2’,3’-e][1,4]diazepin-6-one; NSC 641530-d5

产品性质

• 外观: White Solid
• 熔点: 246-248°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Labelled Nevirapine (N391275), a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Antiviral.

参考文献

• Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991)
• Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1991)
• Guay, L.A., et al.: Lancet, 354, 795 (1991)