Micafungin Sodium

• 产品号: M342350
• CAS号: 208538-73-2
• 分子式: C56H71N9O23S
• 分子量: 1270.27444

产品别名

• 标题: Micafungin Sodium
• IUPAC标准名: {5-[(1S,2S)-2-[(3S,6S,9S,11R,18S,20R,21R,24S,25S,26S)-3-[(1R)-2-carbamoyl-1-hydroxyethyl]-11,20,21,25-tetrahydroxy-15-[(1R)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-18-(4-{5-[4-(pentyloxy)phenyl]-1,2-oxazol-3-yl}benzamido)-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0^9,^1^3]heptacosan-6-yl]-1,2-dihydroxyethyl]-2-hydroxyphenyl}oxidanesulfonic acid
• IUPAC传统名: {5-[(1S,2S)-2-[(3S,6S,9S,11R,18S,20R,21R,24S,25S,26S)-3-[(1R)-2-carbamoyl-1-hydroxyethyl]-11,20,21,25-tetrahydroxy-15-[(1R)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-18-(4-{5-[4-(pentyloxy)phenyl]-1,2-oxazol-3-yl}benzamido)-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0^9,^1^3]heptacosan-6-yl]-1,2-dihydroxyethyl]-2-hydroxyphenyl}oxidanesulfonic acid
• 别名: FK 463; Funguard; 1-[(4R,5R)-4,5-Dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0 Monosodium Salt

产品登记号

• CAS号: 208538-73-2

产品性质

• 外观: Off-White Solid
• 熔点: >211°C (dec.)
• 溶解度: DMSO
• 溶解度: Water

产品详细信息

详细说明 (English)

An echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections.

参考文献

• Chen, S.C. et al.: Drugs, 71, 11 (2011)
• Groll, A.H. et al.: Opin. Anti-Infect. Invest. Drugs, 2, 405 (2011)
• Tomishima, M. et al.: J. Antibiot., 52, 674 (2011)