Mibefradil Dihydrochloride Monohydrate

• 产品号: M341800
• 分子式: C29H40FN3O4
• 分子量: 513.6440032

产品别名

• 标题: Mibefradil Dihydrochloride Monohydrate
• IUPAC标准名: (1S,2S)-2-(2-{[3-(1H-1,3-benzodiazol-2-yl)propyl](methyl)amino}ethyl)-7-fluoro-1-(propan-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate hydrate
• IUPAC传统名: (1S,2S)-2-(2-{[3-(1H-1,3-benzodiazol-2-yl)propyl](methyl)amino}ethyl)-7-fluoro-1-isopropyl-3,4-dihydro-1H-naphthalen-2-yl 2-methoxyacetate hydrate
• 别名: Ro 40-5967 Monohydrate; Methoxyacetic Acid (1S-cis)-2-[2-[[3-(1H-Benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl Ester Dihydrochloride Monohydrate; Ro 40-5967/001 Monohydrate; Posicor Monohydrate; Methoxyacetic Acid (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl Ester Dihydrochloride Monohydrate

产品详细信息

详细说明 (English)

Mibefradil Dihydrochloride is a nondihydropyridine calcium channel blocker with potent vasodilator but weak inotropic action. Mibefradil Dihydrochloride is used in the treatment of hypertension and chronic angina pectoris.

参考文献

• Osterrieder, W. et al.: J. Cardio. Pharmacol., 13, 754 (1989)
• Veniant, M. et al.: J. Cardio. Pharmacol., 21, 544 (1989)
• Hefti, F. et al.: Arzneim.-Forsch., 40, 417 (1989)