MLN 8054-d4

• 产品号: M425127
• 分子式: C25H15ClF2N4O2
• 分子量: 476.8620064

产品别名

• 标题: MLN 8054-d4
• IUPAC标准名: 4-{[13-chloro-10-(2,6-difluorophenyl)-3,5,9-triazatricyclo[9.4.0.0^2,^7]pentadeca-1(11),2(7),3,5,9,12,14-heptaen-4-yl]amino}(^2H₄)benzoic acid
• IUPAC传统名: 4-{[13-chloro-10-(2,6-difluorophenyl)-3,5,9-triazatricyclo[9.4.0.0^2,^7]pentadeca-1(11),2(7),3,5,9,12,14-heptaen-4-yl]amino}(^2H₄)benzoic acid
• 别名: 4-[[9-Chloro-7-(2,6-difluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic Acid-d4

产品详细信息

详细说明 (English)

Labelled MLN 8054 (M425125). An Aurora kinase inhibitor, used to treat patients with advanced solid tumors.

参考文献

• Kaestner, P., et al.: Mol. Cancer Ther., 8, 2046 (2009)
• Scutt, P., et al.: J. Biol. Chem., 284, 15880 (2009)
• Aliagas-Martin, I., et al.: J. Med. Chem., 52, 3300 (2009)