Dextrothyroxine

• 产品号: DB00509
• CAS号: 51-49-0
• 分子式: C15H11I4NO4
• 分子量: 776.87002

产品别名

• 标题: Dextrothyroxine
• IUPAC标准名: 2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
• IUPAC传统名: thyroxine
• 商标名: Eulipos; Choloxin; Dynothel; Lisolipin
• 别名: D-Thyroxine Sodium; Dextrotyroxinnatrium; Dextrothyroxinum Natricum; Sodium 4-O-(4-hydroxy-3,5-di-iodophenyl)-3,5-di-iodo-d-tyrosinate hydrate; 3,5,3′,5′-Tetraiodo-d-thyronine Sodium; Dekstrotyroksiininatrium; Dextrotiroxina sódica

产品登记号

• CAS号: 51-49-0

产品性质

• 疏水性(logP): 4

产品详细信息

详细说明 (English)

• Drug Groups: approved
• Description: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum of stimulatory effects on cell metabolism. [PubChem]
• Indication: Used to lower high cholesterol levels in the blood.
• Pharmacology: Dextrothyroxine, the dextrorotary isomer of the synthetic thyroxine, is a antihyperlipidemic.
• Toxicity: Symptoms of dextrothyroxine overdose are unknown.
• Affected Organisms: Humans and other mammals
• External Links: Wikipedia