2-Methoxy-d3 17β-Estradiol

• 产品号: M262627
• 分子式: C19H26O3
• 分子量: 302.40794

产品别名

• 标题: 2-Methoxy-d3 17β-Estradiol
• IUPAC标准名: (14S,15S)-4-(^2H₃)methoxy-15-methyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2(7),3,5-triene-5,14-diol
• IUPAC传统名: (14S,15S)-4-(^2H₃)methoxy-15-methyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2(7),3,5-triene-5,14-diol
• 别名: 2-Methoxy-d3-estra-1,3,5(10)-triene-3,17β-diol; (17β)-2-Methoxy-d3-estra-1,3,5(10)-triene-3,17-diol; 2-Hydroxyestradiol 2-Methyl-d3 Ether; 2-Methoxy-d3-estradiol; NSC 659853-d3; Panzem-d3

产品性质

• 外观: Crystalline Solid
• 熔点: 188-190°C
• 溶解度: Dichloromethane

产品详细信息

详细说明 (English)

A natural metabolite of 17β-Estradiol which is devoid of estrogenic activity. Inhibits cell proliferation and angiogenesis. Binds to the colchicine binding site of tubulin, and has been suggested to function as a natural regulator of microtubule assembl

参考文献

• Cushman, M., et al.: J. Med. Chem., 38, 2041 (1995)
• D’Amato, R.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 3964 (1995)
• Forsis, T., et al.: Nature, 368, 237 (1994)