Mespirenone

• 产品号: M225770
• CAS号: 87952-98-5
• 分子式: C25H30O4S
• 分子量: 426.5683

产品别名

• 标题: Mespirenone
• IUPAC标准名: (1'R,2S,2'S,3'S,5'S,7'S,10'S,11'R,18'R)-18'-(acetylsulfanyl)-7',11'-dimethylspiro[oxolane-2,6'-pentacyclo[8.8.0.0^2,^7.0^3,^5.0^1^1,^1^6]octadecane]-12',15'-diene-5,14'-dione
• IUPAC传统名: (1'R,2S,2'S,3'S,5'S,7'S,10'S,11'R,18'R)-18'-(acetylsulfanyl)-7',11'-dimethylspiro[oxolane-2,6'-pentacyclo[8.8.0.0^2,^7.0^3,^5.0^1^1,^1^6]octadecane]-12',15'-diene-5,14'-dione
• 别名: ZK 94679; (7α,15α,16α,17α)-7-(Acetylthio)-15,16-dihydro-17-hydroxy-3-oxo-3'H-cyclopropa[15,16]pregna-1,4,15-triene-21-carboxylic Acid γ-Lactone

产品登记号

• CAS号: 87952-98-5

产品详细信息

详细说明 (English)

A new mineralocorticoid antagonist; has an inhibition effect on aldosterone-induced hypertension.

参考文献

• Hildebrand, M., et al.: Xenobiotica, 17, 623 (1987)
• Nishino, Y., et al.: Arzneim.-Forsch., 38, 1800 (1987)
• Zhao, Y., et al.: J. Pharm. Sci., 90, 749 (1987)
• Chiou, W., et al.: Pharm. Res., 19, 868 ( 2002),