Mafosfamide Sodium Salt

• 产品号: M110300
• CAS号: 84211-05-2
• 分子式: C9H18Cl2N2NaO5PS2
• 分子量: 423.249151
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Mafosfamide Sodium Salt
• IUPAC标准名: sodium 2-{[(2R,4R)-2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2λ^5-oxazaphosphinan-4-yl]sulfanyl}ethane-1-sulfonate
• IUPAC传统名: sodium 2-{[(2R,4R)-2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2λ^5-oxazaphosphinan-4-yl]sulfanyl}ethanesulfonate
• 别名: Mafosfamid Sodium; rel-2-[[(2R,4R)-2-[Bis(2-chloroethyl)amino]tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-4-yl]thio]ethanesulfonic Acid Sodium; cis-Mafosfamide Sodium; Z 7557

产品登记号

• CAS号: 84211-05-2

产品性质

• 外观: White Solid
• 熔点: >145°C (dec.)
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A Cyclophosphamide analog which induces apoptosis dose and time dependently in lymphoblastoid cells, with clearly more apoptosis in p53wt cells. Antitumor agent.

参考文献

• Roy, P., et al.: Drug Metab. Dispos., 27, 655 (1999)
• Lips, J., et al.: Carcinogenesis, 22, 579 (1999)
• Ward, I., et al.: J. Biol. Chem., 276, 47759 (1999)
• Zhou, B., et al.: Cancer Biol. Ther., 2, S16 (1999)
• Roos, W., et al.: Oncogene, 26, 186 (1999)