β-Lumi (-)-Colchicine

• 产品号: L474300
• CAS号: 6901-13-9
• 分子式: C22H25NO6
• 分子量: 399.437
• 保 存: Amber Vial, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: β-Lumi (-)-Colchicine
• IUPAC标准名: N-[(10S,12R,16S)-3,4,5,14-tetramethoxy-13-oxotetracyclo[9.5.0.0^2,^7.0^1^2,^1^6]hexadeca-1(11),2(7),3,5,14-pentaen-10-yl]acetamide
• IUPAC传统名: N-[(10S,12R,16S)-3,4,5,14-tetramethoxy-13-oxotetracyclo[9.5.0.0^2,^7.0^1^2,^1^6]hexadeca-1(11),2(7),3,5,14-pentaen-10-yl]acetamide
• 别名: Lumicolchicine; β-Lumi-(-)-colchicine; NSC 56233; N-[(7S,7bR,10aS)-5,6,7,7b,8,10a-Hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl]acetamide; β-Lumicolchicine; (-)-β-Lumicolchicine; NSC 221661

产品登记号

• CAS号: 6901-13-9

产品性质

• 外观: Pale Yellow Solid
• 熔点: 177-180°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: Amber Vial, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

An analog of Colchicine (C640000), β-lumicolchicine, does not bind tubulin or disrupt microtubules. A GABAA receptor chloride channel.

参考文献

• Andreu, J., et al.: Biochemistry, 37, 8356 (1998)
• Weiner, J., et al.: J. Pharmacol. Exp. Ther., 284, 95 (1998)
• Hong, G., et al.: J. Pharm. Sci., 88, 147 (1998)