Lovastatin Diol Lactone 4-tert-Butyldimethylsilyl Ether

• 产品号: L472240
• CAS号: 79902-31-1
• 分子式: C25H42O4Si
• 分子量: 434.68408

产品别名

• 标题: Lovastatin Diol Lactone 4-tert-Butyldimethylsilyl Ether
• IUPAC标准名: (4R,6R)-6-{2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}-4-[(tert-butyldimethylsilyl)oxy]oxan-2-one
• IUPAC传统名: (4R,6R)-6-{2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}-4-[(tert-butyldimethylsilyl)oxy]oxan-2-one
• 别名: (4R,6R)-4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-6-[2-[(1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl]ethyl]tetrahydro-2H-pyran-2-one

产品登记号

• CAS号: 79902-31-1

产品性质

• 外观: White Solid
• 溶解度: Dichloromethane
• 溶解度: DMF
• 溶解度: DMSO
• 溶解度: Ether
• 溶解度: Ethyl Acetate
• 溶解度: Methanol

产品详细信息

详细说明 (English)

An intermediate used for synthesis of Simvastatin precursor (H941625).

参考文献

• Hoffman, W., et al.: J. Med. Chem., 29, 849 (1986)
• Jacobsen, W., et al.: Drug Metab. Dispos., 27, 173 (1986)
• Igel, M., et al.: Eur. J. Clin. Pharmacol., 57, 357 (1986)