(+/-)-Lisofylline-d6

• 产品号: L469053
• 分子式: C13H20N4O3
• 分子量: 280.3229

产品别名

• 标题: (+/-)-Lisofylline-d6
• IUPAC标准名: 1-[5-hydroxy(4,4,5,6,6,6-^2H₆)hexyl]-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
• IUPAC传统名: 1-[5-hydroxy(4,4,5,6,6,6-^2H₆)hexyl]-3,7-dimethylpurine-2,6-dione
• 别名: Pentoxifylline-d6 Alcohol; 3,7-Dihydro-1-(5-hydroxyhexyl-d6)-3,7-dimethyl-1H-purine-2,6-dione; (+/-)-1-(5-Hydroxyhexyl-d6)-3,7-dimethylxanthine; 1-(5-Hydroxyhexyl-d6)theobromine; BL 194-d6

产品详细信息

详细说明 (English)

A major oxidative labelled metabolite of Pentoxifylline. A potent inhibitor of phosphatidic acid generation (IC50=0.6uM). Protects mice from endotoxic shock and attenuates sepsis-induced acute lung injury in pig.

参考文献

• Clarke, E., et al.: Cancer Res., et al.: 56, 105 (1996)
• Itani, S., et al.: Metabolism, 50, 553 (1996)
• Itani, S., et al.: Diabetes, 51, 2005(1996)
• Yu, C., et al.: J. Biol. Chem., 277, 50230 (1996)