Linagliptin

• 产品号: L465900
• CAS号: 668270-12-0
• 分子式: C25H28N8O2
• 分子量: 472.54222
• 保 存: Refrigerator

产品别名

• 标题: Linagliptin
• IUPAC标准名: 8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,3,6,7-tetrahydro-1H-purine-2,6-dione
• IUPAC传统名: linagliptin
• 别名: BI 1356BS; 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione; BI 1356; ONDERO; 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione

产品登记号

• CAS号: 668270-12-0

产品性质

• 外观: Yellowish Orange Solid
• 熔点: 190-196°C (dec.)
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

A novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.

参考文献

• Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011)
• Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011)