LG 100268

• 产品号: L397650
• CAS号: 153559-76-3
• 分子式: C24H29NO2
• 分子量: 363.49256
• 保 存: -20°C Freezer

产品别名

• 标题: LG 100268
• IUPAC标准名: 6-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]pyridine-3-carboxylic acid
• IUPAC传统名: 6-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)cyclopropyl]pyridine-3-carboxylic acid
• 别名: LGD 100268; LGD 1268; ALRT 268; CD 3127; 6-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]-3-Pyridinecarboxylic Acid; AGN 192620; LG 268

产品登记号

• CAS号: 153559-76-3

产品性质

• 外观: Off-White Solid
• 熔点: 275-277°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

LG 100268 is a potent RXR agonist for evaluation in the treatment of non-insulin-dependent (type II) diabetes mellitus (NIDDM).

参考文献

• Clyne, C., et al.: J. Biol. Chem., 277, 20591 (2002)
• Santen, R., et al.: J. Clin. Endocrinol. Metab., 87, 3007 (2002)
• Falender, A., et al.: Endocrinology, 144, 3598 (2002)
• Sablin, E., et al.: Mol. Cell., 11, 1575 (2003)