Leurosine Sulfate

• 产品号: L330800
• CAS号: 54081-68-4
• 分子式: C46H56N4O9
• 分子量: 808.95824
• 保 存: -20°C Freezer

产品别名

• 标题: Leurosine Sulfate
• IUPAC标准名: methyl (13S,15R,16R,18S)-13-[(1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2(7),3,5,13-tetraen-4-yl]-18-ethyl-17-oxa-1,11-diazapentacyclo[13.4.1.0^4,^1^2.0^5,^1^0.0^1^6,^1^8]icosa-4(12),5,7,9-tetraene-13-carboxylate
• IUPAC传统名: methyl (1S,13S,15R,16R,18S)-13-[(1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2(7),3,5,13-tetraen-4-yl]-18-ethyl-17-oxa-1,11-diazapentacyclo[13.4.1.0^4,^1^2.0^5,^1^0.0^1^6,^1^8]icosa-4(12),5,7,9-tetraene-13-carboxylate
• 别名: Lilly 32645; Vinleurosine Sulfate; 4β-Acetoxy-3’α,4’-epoxy-3-hydroxy-16-methoxy-(4’α H)-vincaleukoblast-6-ene-23,22’-dioic Acid Dimethyl Ester Sulfate

产品登记号

• CAS号: 54081-68-4

产品性质

• 外观: Light Yellow Solid
• 熔点: >200°C (dec.)
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A new antitumor derivative of Vinblastine; a dimeric Vinca alkaloid for cancer therapy.

参考文献

• Chakravarty, et al.: J. Med. Chem., 26(5)
• 638 (5)
• Christensson., et al.: Eu.r J. Biochem., 194, 755 (5)
• Mayer, et al.: J. Med. Chem., 34, 3029 (5)
• Yu, H., et al.: Clin. Biochem., 27, 75 (1994)