Letaxaban-d5

• 产品号: L329852
• 分子式: C22H26ClN3O5S
• 分子量: 479.97694

产品别名

• 标题: Letaxaban-d5
• IUPAC标准名: 1-{1-[(2S)-3-[(6-chloronaphthalen-2-yl)sulfonyl]-2-hydroxypropanoyl](3,3,4,5,5-^2H₅)piperidin-4-yl}-1,3-diazinan-2-one
• IUPAC传统名: 1-{1-[(2S)-3-(6-chloronaphthalen-2-ylsulfonyl)-2-hydroxypropanoyl](3,3,4,5,5-^2H₅)piperidin-4-yl}-1,3-diazinan-2-one
• 别名: 1-[(2S)-3-[(6-Chloro-2-naphthalenyl)sulfonyl]-2-hydroxy-1-oxopropyl]-4-(tetrahydro-2-oxo-1(2H)-pyrimidinyl)piperidine-d5; TAK 442-d5; 1-[1-[(2S)-3-[(6-Chloronaphthalen-2-yl)sulfonyl]-2-hydroxypropanoyl](piperidin-4-yl-d5)]tetrahydropyrimidin-2(1H)-one; 1-[1-[(2S)-3-[(6-chloro-2-naphthalenyl)sulfonyl]-2-hydroxy-1-oxopropyl]-4-(piperidinyl-d5)]tetrahydro-2(1H)-pyrimidinone

产品详细信息

详细说明 (English)

A labelled potent and selective orally active factor Xa (FXa) inhibitor; anticoagulant. Effective in preventing venous thromboembolism in patient undergoing orthopedic surgery.

参考文献

• Zufferey, P.J. et al.: Thromb. Haemost., 104, 1083 (2010)
• Kawamura, M. et al.: J. Cardio. Pharmacol., 56, 156 (2010)
• Fujimoto, T. et al.: J. Med. Chem., 53, 3517 (2010)