Lapatinib-13C2,15N Ditosylate

• 产品号: L175802
• 分子式: C36H34ClFN4O7S2
• 分子量: 756.23788177
• 保 存: -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Lapatinib-13C2,15N Ditosylate
• IUPAC标准名: 4-methylbenzene-1-sulfonic acid; N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-[5-({[2-methanesulfonyl(1,2-^1^3C₂)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine
• IUPAC传统名: N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-[5-({[2-methanesulfonyl(1,2-^1^3C₂)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine; toluenesulfonic acid
• 别名: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine Bis(4-methylbenzenesulfonate)-13C2,15N Ditosylate; GW-572016F-13C2,15N; Tykerb-13C2,15N Ditosylate

产品性质

• 外观: Yellow Solid
• 熔点: 247-249°C
• 溶解度: DMSO
• 保存条件: -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

Labelled Lapatinib (L175800). Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic.

参考文献

• Kim, T.E., et al.: Drugs, 6, 886 (2003)
• Wood, E.R., et al.: Cancer Res., 64, 6652 (2003)
• Spector, N.L., et al.: J. Clin. Oncol., 23, 2502 (2003)