KO 143

• 产品号: K655000
• CAS号: 461054-93-3
• 分子式: C26H35N3O5
• 分子量: 469.5732

产品别名

• 标题: KO 143
• IUPAC标准名: tert-butyl 3-[(2S,5S,8S)-14-methoxy-2-(2-methylpropyl)-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0^3,^8.0^1^1,^1^6]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate
• IUPAC传统名: tert-butyl 3-[(2S,5S,8S)-14-methoxy-2-(2-methylpropyl)-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.0^3,^8.0^1^1,^1^6]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate
• 别名: (3S,6S,12aS)-,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic Acid 1,1-Dimethylethyl Ester

产品登记号

• CAS号: 461054-93-3

产品详细信息

详细说明 (English)

A potent BCRP (breast cancer resistance protein) inhibitor.

参考文献

• Allen, J., et al.: Cancer Res., 59, 4237 (1999)
• van Loevezijn, A., et al.: Bioorg. Med. Chem. Lett., 11, 29 (1999)
• Raaijmakers, M., et al.: Clin. Cancer Res., 11, 2436 (1999)