Kifunensine

• 产品号: K450000
• CAS号: 109944-15-2
• 分子式: C8H12N2O6
• 分子量: 232.19068
• 保 存: -20°C Freezer

产品别名

• 标题: Kifunensine
• IUPAC标准名: (5R,6R,7S,8R,8aS)-6,7,8-trihydroxy-5-(hydroxymethyl)-octahydroimidazolidino[1,2-a]pyridine-2,3-dione
• IUPAC传统名: (5R,6R,7S,8R,8aS)-6,7,8-trihydroxy-5-(hydroxymethyl)-hexahydroimidazolidino[1,2-a]pyridine-2,3-dione
• 别名: FR 900494; [5R-(5α,6β,7α,8α,8aα)]-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione; (+)-Kifunensine

产品登记号

• CAS号: 109944-15-2

产品性质

• 外观: White Solid
• 熔点: >280°C (dec.)
• 溶解度: DMSO
• 溶解度: Hot Water
• 保存条件: -20°C Freezer
• 保存注意事项: Desiccate and Store at -20°C

产品详细信息

详细说明 (English)

Kifunensine is an alkaloid produced by the fungus, Kitasatosporia kifunense, and has been shown to be a weak inhibitor of aryl mannosidase. It is a unique oxamide derivative of mannojirimycin and a potent inhibitor of the glycoprotein processing enzyme

参考文献

• Kayakiri, H., et al.: Chem. Pharm. Bull., 39(1987)
• 1378 (1991)
• Iwami, M., et al.: J. Antibiotic., 40, 612 (1987)
• Elbein, A.D., et al.: J. Biol. Chem., 265, 15599 (1987)
• Elbein, A.D., et al.: Archives of Biochem & Biophys., 288, 1, 177 (1987)