K201

• 产品号: K000400
• CAS号: 1026399-42-7
• 分子式: C26H33NO2S
• 分子量: 423.61072

产品别名

• 标题: K201
• IUPAC标准名: 3-(4-benzylcyclohexyl)-1-(7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepin-4-yl)propan-1-one
• IUPAC传统名: 3-(4-benzylcyclohexyl)-1-(7-methoxy-3,5-dihydro-2H-1,4-benzothiazepin-4-yl)propan-1-one
• 别名: JTV-519; 1-(2,3-Dihydro-7-methoxy-1,4-benzothiazepin-4(5H)-yl)-3-[4-(phenylmethyl)cyclohexyl]-1-propanone

产品登记号

• CAS号: 1026399-42-7

产品详细信息

详细说明 (English)

K201 is a benzothiazepine derivative that has been shown to possess anti-arrhythmic and cardioprotective properties. Recent studies suggest that suppression of spontaneous Ca2+ release and the activity of RyR2 contributes, at least in part, to the anti-ar

参考文献

• Hunt, D.J. et al.: Biochem. J., 404, 431 (2007)
• Toisher, K. et al.: Basic Res. Cardiol., 105, 279 (2007)