Iso-FK-506 (iso-Tacrolimus)

• 产品号: I816250
• CAS号: 134590-88-8
• 分子式: C44H69NO12
• 分子量: 804.01816
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Iso-FK-506 (iso-Tacrolimus)
• IUPAC标准名: (1R,9S,12S,15R,16E,19S,21S,22R,23R,25R)-1-hydroxy-12-[(2S,3S,4E)-3-hydroxy-5-[(1R,3S,4R)-4-hydroxy-3-methoxycyclohexyl]-4-methylpent-4-en-2-yl]-21,23-dimethoxy-17,19,25-trimethyl-15-(prop-2-en-1-yl)-11,26-dioxa-4-azatricyclo[20.3.1.0^4,^9]hexacos-16-ene-2,3,10,14-tetrone
• IUPAC传统名: (1R,9S,12S,15R,16E,19S,21S,22R,23R,25R)-1-hydroxy-12-[(2S,3S,4E)-3-hydroxy-5-[(1R,3S,4R)-4-hydroxy-3-methoxycyclohexyl]-4-methylpent-4-en-2-yl]-21,23-dimethoxy-17,19,25-trimethyl-15-(prop-2-en-1-yl)-11,26-dioxa-4-azatricyclo[20.3.1.0^4,^9]hexacos-16-ene-2,3,10,14-tetrone
• 别名: [3S-[3R*[1R*,2R*,4(1S*,3S*,4S*)],6S*,10R*,12R*,13R*,14R*,16S*,17S*,24aR*]]-6,9,10,11,12,13,14,15,16,17,22,23,24,24a-tetradecahydro-17-hydroxy-3-[2-hydroxy-4-(4-hydroxy-3-methoxycyclohexyl)-1,3-dimethyl-3-butenyl]-12,14-dimethoxy-8,10,16-trimethyl-6-(2-propenyl)-13,17-epoxy-3H-pyrido[2,1-c][1,4]oxaazacycloheneicosine-1,5,18,19(4H,21H)-tetrone

产品登记号

• CAS号: 134590-88-8

产品性质

• 外观: White Solid
• 熔点: 82-87°C
• 溶解度: Chloroform
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

An isomer of FK-506 (F370000) from fermentation of Streptomyces tsukubaensis, as immunosuppressant and antiinflammatory agent.

参考文献

• Grassberger, M.A., et al.: Tetrahedron, 48, 413 (1992)