Isavuconazole-d4

• 产品号: I777832
• 分子式: C22H17F2N5OS
• 分子量: 437.4650864

产品别名

• 标题: Isavuconazole-d4
• IUPAC标准名: 4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}(^2H₄)benzonitrile
• IUPAC传统名: 4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}(^2H₄)benzonitrile
• 别名: RO 0094815-d4; BAL 4815-d4; 2R,3R)-3-[4-(4-Cyanophenyl)thiazol-2-yl]-2-(2,5-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol-d4; 4-[2-[(1R,2R)-2-(2,5-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile-d4

产品详细信息

详细说明 (English)

Labelled Isavuconazole (I777832). It is a new triazole currently undergoing phase III clinical trials. This compound has shown in vitro activity against a large number of clinical important yeasts and molds including Aspergillus spp., Fusarium spp., Scedo

参考文献

• Ohwada, J., et al.: Bioorg. Med. Chem. Lett., 13, 191 (2003)
• Guinea, J., et al.: Antimicrob. Agents Chemother., 52, 1396 (2008)