Irinotecan Lactone Impurity

• 产品号: I767520
• CAS号: 143490-53-3
• 分子式: C32H36N4O5
• 分子量: 556.65204

产品别名

• 标题: Irinotecan Lactone Impurity
• IUPAC标准名: 5,13-diethyl-7,9-dioxo-6-oxa-10,20-diazapentacyclo[10.8.0.0^2,^1^0.0^4,^8.0^1^4,^1^9]icosa-1(20),2,4(8),12,14,16,18-heptaen-16-yl 4-(piperidin-1-yl)piperidine-1-carboxylate
• IUPAC传统名: 5,13-diethyl-7,9-dioxo-6-oxa-10,20-diazapentacyclo[10.8.0.0^2,^1^0.0^4,^8.0^1^4,^1^9]icosa-1(20),2,4(8),12,14,16,18-heptaen-16-yl 4-(piperidin-1-yl)piperidine-1-carboxylate
• 别名: [1,4'-Bipiperidine]-1'-carboxylic Acid 3,10-Diethyl-11,13-dihydro-1,13-dioxo-1H,3H- furo[3',4':6,7]indolizino[1,2-b]quinolin-8-yl Ester

产品登记号

• CAS号: 143490-53-3

产品详细信息

详细说明 (English)

A lactone impurity of Irinotecan (I767500), a DNA topoisomerase inhibitor. A photodegradation product of a camptothecin derivative used as an anticancer drug.

参考文献

• Akimoto, K. et al.: J. Chrom. 734, 401 (1996)
• Kunimoto, T., et al.: Cancer Res., 47, 5944 (1996)
• Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1996)
• Chen, A., et al.: Annu. Rev. Pharmacol. Toxicol., 34, 191 (1996)