Irinotecan Carboxylate Sodium Salt

• 产品号: I767510
• 分子式: C33H39N4NaO7
• 分子量: 626.67513
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Irinotecan Carboxylate Sodium Salt
• IUPAC标准名: sodium (2S)-2-[12-ethyl-8-(hydroxymethyl)-9-oxo-2-[4-(piperidin-1-yl)piperidine-1-carbonyloxy]-9H,11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoate
• IUPAC传统名: sodium cpt-11 carboxylate form
• 别名: (αS)-2-[([1,4'-Bipiperidin]-1'-ylcarbonyl)oxy]-α,12-diethyl-9,11-dihydro-α-hydroxy-8-(hydroxymethyl)-9-oxo-indolizino[1,2-b]quinoline-7-acetic Acid Sodium Salt; CPT 11 Carboxylic Acid Sodium Salt

产品性质

• 外观: Off-White to Pale Yellow Solid
• 熔点: 177-183°C
• 溶解度: DMSO
• 溶解度: Water
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

Carboxylate form of Irinotecan, a DNA topoisomerase inhibitor.

参考文献

• Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987)
• Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1987)
• Chen, A., et al.: Annu. Rev. Pharmacol. Toxicol., 34, 191 (1987)