5-Iodotubercidin

• 产品号: I725000
• CAS号: 24386-93-4
• 分子式: C11H13IN4O4
• 分子量: 392.14979
• 保 存: -20°C Freezer

产品别名

• 标题: 5-Iodotubercidin
• IUPAC标准名: (2R,3S,5R)-2-{4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol
• IUPAC传统名: (2R,3S,5R)-2-{4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol
• 别名: 7-Iodotubercidin; 4-Amino-5-iodo-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; NSC 113939 5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

产品登记号

• CAS号: 24386-93-4

产品性质

• 外观: White to Off-White Solid
• 熔点: 216-217°C dec.
• 溶解度: DMSO
• 保存条件: -20°C Freezer
• 保存注意事项: Store tightly sealed at 4°C; Light Sensitive

产品详细信息

详细说明 (English)

An analogue of the antibiotic tubercidin, a pyrrolo[2,3-d]pyrimidine nucleoside antibiotic. A potent inhibitor of adenosine kinase from rat or guinea pig brain. Inhibits uptake of 3H-adenosine into brain slices.

参考文献

• Long, M., et al.: Biochem. Pharmacol., 71, 1671 (2006)
• Lehar, J., et al.: Mol. Sys. Biol., (2006)
• Bonilla-Santiago, R., et al.: Mol. Biochem. Parasitol., 162, 149 (2006)
• Caballero, J., et al.: Bioorg. Med. Chem., 16, 5103 (2006)