Indomethacin Acyl-β-D-glucuronide

• 产品号: I641010
• CAS号: 75523-11-4
• 分子式: C25H24ClNO10
• 分子量: 533.91176
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Indomethacin Acyl-β-D-glucuronide
• IUPAC标准名: (2R,3R,4R,5S,6R)-6-({2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC传统名: (2R,3R,4R,5S,6R)-6-({2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
• 别名: 1-[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate] β-D-Glucopyranuronic Acid; Indomethacin Glucuronide

产品登记号

• CAS号: 75523-11-4

产品性质

• 外观: Light-Green Solid
• 熔点: 82-84°C
• 溶解度: Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

Indomethacin Acyl-β-D-glucuronide is a metabolite of Indomethacin (I641000). Acyl glucuronides have been implicated in the toxicity of many xenobiotics and marketed drugs.

参考文献

• Abid, A., et al.: Biochem. Pharmacol., 50, 557 (1995)
• Gamage, N., et al.: Toxicol. Sci., 90, 5 (1995)
• Cerveny, L., et al.: Drug Metab. Dispos., 35, 1032 (1995)
• Hayeshi, R., et al.: Eur. J. Pharm. Sci., 35, 383 (1995)