Imatinib (Piperidine)-N,N-dioxide

• 产品号: I268020
• CAS号: 571186-93-1
• 分子式: C29H31N7O3
• 分子量: 525.60154

产品别名

• 标题: Imatinib (Piperidine)-N,N-dioxide
• IUPAC标准名: 1-methyl-4-({4-[(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)carbamoyl]phenyl}methyl)piperazine-1,4-diium-1,4-bis(olate)
• IUPAC传统名: 1-methyl-4-({4-[(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)carbamoyl]phenyl}methyl)piperazine-1,4-diium-1,4-bis(olate)
• 别名: 4-[(4-Methyl-1,4-dioxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide

产品登记号

• CAS号: 571186-93-1

产品详细信息

详细说明 (English)

Imatinib (Piperidine)-N,N-dioxide is an impurity of Imatinib (Gleevec) (G407000). Imatinib impurity B.

参考文献

• Taruns, C., et al.: Bioorg. Chem., 16, 38 (1988)
• Cohen, M., et al.: Clin. Cancer Res., 8, 935 (1988)
• Gschwind, H., et al.: Drug Metab. Dispos., 33, 1503 (1988)
• Peng, B., et al.: Clin. Pharmacokinet., 44, 879 (1988)