Iloprost

• 产品号: I267300
• CAS号: 78919-13-8
• 分子式: C22H32O4
• 分子量: 360.48708

产品别名

• 标题: Iloprost
• IUPAC标准名: 5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid
• IUPAC传统名: iloprostum
• 别名: Ciloprost; (5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic Acid; ZK 36374; Endoprost; (1S,2R,3R,5S)-7-[(E)-4-Carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyn-1-enyl]-bicyclo[3.3.0]octane; Ilomedin

产品登记号

• CAS号: 78919-13-8

产品详细信息

详细说明 (English)

A synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia. It acts through elevation of cAMP by binding to the prostacyclin receptor (IP receptor). Iloprost inhibits the

参考文献

• Zamudio, T.P.: Arch. Cardiol. Mex., 77, 198 (2007)
• Lai, Y. et al.: Am. J. Resp. Crit. Care Med., 178, 188 (2007)
• Scorza, R. et al.: J. Rheutamol., 24, 1944 (2007)
• Melillo, E. et al.: Int. J. Microcircul. Clin. Exp., 15, 60 (2007)