ICI 118551 Hydrochloride

• 产品号: I163850
• CAS号: 72795-01-8
• 分子式: C17H28ClNO2
• 分子量: 313.86272

产品别名

• 标题: ICI 118551 Hydrochloride
• IUPAC标准名: (2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-[(propan-2-yl)amino]butan-2-ol hydrochloride
• IUPAC传统名: (2R,3S)-3-(isopropylamino)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]butan-2-ol hydrochloride
• 别名: ICI 111581; (R*,R*)-1-[(2,3-Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol Hydrochloride; (2R,3R)-rel-1-[(2,3-Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol Hydrochloride

产品登记号

• CAS号: 72795-01-8

产品详细信息

详细说明 (English)

The (R,R)-enantiomer of ICI 118551 as highly selective β2-adrenoceptor antagonist. The S,S-enantiomer is the most potent.

参考文献

• Bilski, A., et al.: J. Cardiovasc. Pharmacol., 5, 430 (1983)
• Furse, K., et al.: J. Med. Chem., 46, 4450 (1983)
• Cherezov, V., et al.: Science, 318, 1258 (1983)