(S,S)-ICG 001

• 产品号: I163800
• CAS号: 780757-88-2
• 分子式: C33H32N4O4
• 分子量: 548.63158

产品别名

• 标题: (S,S)-ICG 001
• IUPAC标准名: (6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-8-(naphthalen-1-ylmethyl)-4,7-dioxo-octahydro-1H-pyrimido[1,2-a]piperazine-1-carboxamide
• IUPAC传统名: (6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-8-(naphthalen-1-ylmethyl)-4,7-dioxo-tetrahydro-2H-pyrimido[1,2-a]piperazine-1-carboxamide
• 别名: (6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide

产品登记号

• CAS号: 780757-88-2

产品详细信息

详细说明 (English)

(S,S)-ICG 001 is a β-turn peptidomimetic molecule inhibitor of β-catenin-Tcf-mediated transcription.

参考文献

• McMillan, M., et al.: Drug Discov. Today, 10, 1467 (2005)
• Brantjes, H., et al.: Biol. Chem., 383, 255 (2005)
• Nusse, R., et al.: Cell Res., 15, 28 (2005)
• Eguchi, M., et al.: Med. Chem., 1, 467 (2005)