Hymenialdisine Analogue #1

• 产品号: H998025
• CAS号: 693222-51-4
• 分子式: C15H13N5O2
• 分子量: 295.29602
• 保 存: -20°C Freezer

产品别名

• 标题: Hymenialdisine Analogue #1
• IUPAC标准名: 2-amino-4-{1-oxo-1H,2H,3H,4H,5H,10H-azepino[3,4-b]indol-5-ylidene}-4,5-dihydro-1H-imidazol-5-one
• IUPAC传统名: 2-amino-5-{1-oxo-2H,3H,4H,10H-azepino[3,4-b]indol-5-ylidene}-3H-imidazol-4-one
• 别名: 5-(2-Amino-5-oxo-1,5-dihydroimidazol-4-ylidene)-3,4,5,10-tetrahydro-2H-azepino[3,4-b]indol-1-one

产品登记号

• CAS号: 693222-51-4

产品性质

• 外观: Light Yellow Solid
• 溶解度: Butanol
• 溶解度: DMSO
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

The indole derivative of Hymenialdisine, a potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. This compound exhibits very potent inhibi

参考文献

• Sharma, V., and Tepe, J.J.: Bioorg. & Medicinal Chem. Letters, 14, 4319 (2004)
• Sharma, V., et al.: J. Med. Chem., 47, 3700 (2004)