3'-p-Hydroxy Paclitaxel-d5

• 产品号: H948897
• 分子式: C47H51NO15
• 分子量: 869.90554
• 保 存: -20°C Freezer

产品别名

• 标题: 3'-p-Hydroxy Paclitaxel-d5
• IUPAC标准名: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-(4-hydroxyphenyl)-3-[(^2H₅)phenylformamido]propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC传统名: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-(4-hydroxyphenyl)-3-[(^2H₅)phenylformamido]propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate

产品性质

• 外观: Off-White Solid
• 熔点: 181-189°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A labelled metabolite of Paclitaxel; a phase I pharmacokinetic study in patients with solid tumors.

参考文献

• Sonnichsen, D., et al.: J. Pharmacol. Exp. Ther., 275, 566 (1995)
• Walle, T., et al.: Drug Metab. Dispos., 23, 506 (1995)
• Torres, K., et al.: Cancer Res., 58, 3620 (1995)
• Svojanovsky, S., et al.: J. Pharm. Biomed. Anal., 20, 549 (1995)