5-(Hydroxymethyl)-2'-deoxycytidine-d3

• 产品号: H946632
• 分子式: C10H15N3O5
• 分子量: 257.2432
• 保 存: Refrigerator

产品别名

• 标题: 5-(Hydroxymethyl)-2'-deoxycytidine-d3
• IUPAC标准名: 4-amino-5-[hydroxy(^2H₂)methyl]-1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro(^2H)pyrimidin-2-one
• IUPAC传统名: 4-amino-5-[hydroxy(^2H₂)methyl]-1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl](^2H)pyrimidin-2-one
• 别名: 5-(Hydroxymethyl)deoxycytidine-d3; 2'-deoxy-5-(hydroxymethyl)cytidine-d3

产品性质

• 外观: White Solid
• 熔点: 200-202°C
• 溶解度: DMSO
• 溶解度: Water
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

Labelled 4-(Hydroxymethyl)-2’-deoxycytidine, a modified pyrimidine that is capable of producing interstrand cross-links in duplex DNA. 4-(Hydroxymethyl)-2’-deoxycytidine can be analyzed to quantify DNA hydroxymethylation levels in biological samples.

参考文献

• Peng, X. et al.: J. Am. Chem. Soc., 130, 10299 (2008)
• Berkner, K. et al.: J. Biol. Chem., 252, 3185 (2008)
• Le, T. et al.: Anal. Biochem., 412, 203 (2008)