5-(Hydroxymethyl)-2'-deoxycytidine

• 产品号: H946630
• CAS号: 7226-77-9
• 分子式: C10H15N3O5
• 分子量: 257.2432

产品别名

• 标题: 5-(Hydroxymethyl)-2'-deoxycytidine
• IUPAC标准名: 4-amino-1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)-1,2-dihydropyrimidin-2-one
• IUPAC传统名: 4-amino-1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)pyrimidin-2-one
• 别名: 5-(Hydroxymethyl)deoxycytidine; 2'-deoxy-5-(hydroxymethyl)cytidine

产品登记号

• CAS号: 7226-77-9

产品详细信息

详细说明 (English)

4-(Hydroxymethyl)-2’-deoxycytidine is a modified pyrimidine that is capable of producing interstrand cross-links in duplex DNA. 4-(Hydroxymethyl)-2’-deoxycytidine can be analyzed to quantify DNA hydroxymethylation levels in biological samples

参考文献

• Peng, X. et al.: J. Am. Chem. Soc., 130, 10299 (2008)
• Berkner, K. et al.: J. Biol. Chem., 252, 3185 (2008)
• Le, T. et al.: Anal. Biochem., 412, 203 (2008)