12-Hydroxy Irinotecan

• 产品号: H943545
• CAS号: 185336-12-3
• 分子式: C33H38N4O7
• 分子量: 602.67742

产品别名

• 标题: 12-Hydroxy Irinotecan
• IUPAC标准名: (19S)-10,19-diethyl-12,19-dihydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate
• IUPAC传统名: (19S)-10,19-diethyl-12,19-dihydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2,4,6,8,10,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate
• 别名: RPR 112524; (4S)-4,11-Diethyl-4,12-dihydroxy-9-[(4-piperidinopiperidino)carbonyloxy]-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; [1,4'-Bipiperidine]-1'-carboxylic Acid (4S)-4,11-diethyl-3,4,12,14-tetrahydro- 4,12-dihydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl Ester; Irinotecan 12-Hydroxy Impurity

产品登记号

• CAS号: 185336-12-3

产品详细信息

详细说明 (English)

A metabolite of Irinotecan (I767500) found in human bile and urine.

参考文献

• Lokeic, F. et al.: Clin. Cancer Res., 2, 1943 (1996)
• Dodds, H.M. et al.: Anti-cancer Drug Des., 16, 239 (1996)
• Kunimoto, T., et al.: Cancer Res., 47, 5944 (1996)
• Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1996)