rac 7-Hydroxy Efavirenz-d4 (Major)

• 产品号: H941822
• 分子式: C14H9ClF3NO3
• 分子量: 331.6743696
• 保 存: -20°C Freezer

产品别名

• 标题: rac 7-Hydroxy Efavirenz-d4 (Major)
• IUPAC标准名: 6-chloro-4-{2-[(2,2,3,3-^2H₄)cyclopropyl]ethynyl}-7-hydroxy-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one
• IUPAC传统名: 6-chloro-4-{2-[(2,2,3,3-^2H₄)cyclopropyl]ethynyl}-7-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
• 别名: 6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-7-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one

产品性质

• 外观: Off-White Solid
• 熔点: >194°C (dec.)
• 溶解度: DMSO
• 溶解度: Ethyl Actetae
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

An isotope labelled metabolite of Efavirenz (E425000) (minor).A representative lot was 84% d4, 12% d5, 2% d3 and 1% d6.

参考文献

• Gorski, J., et al.: Biochem. Pharmacol., 47, 1643 (1994)
• Desta, Z., et al.: J. Pharmacol. Exp. Ther., 285, 428 (1994)
• Langmann, P., et al.: Eur. J. Med. Res., 7, 309 (1994)
• Chang, T., et al.: Drug Metab. Dispos., 31, 7 (1994)