6(R)-[2-(8(S)-Hydroxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one

• 产品号: H941625
• CAS号: 79952-42-4
• 分子式: C19H28O4
• 分子量: 320.42322
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: 6(R)-[2-(8(S)-Hydroxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one
• IUPAC标准名: (4R,6R)-6-{2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}-4-hydroxyoxan-2-one
• IUPAC传统名: (4R,6R)-6-{2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}-4-hydroxyoxan-2-one
• 别名: Lovastatin Diol Lactone; Monacolin J; (4R,6R)-6-[2-[(1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-Hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl]ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one; Antibiotic MB 530A

产品登记号

• CAS号: 79952-42-4

产品性质

• 外观: White Solid
• 熔点: 109-114°C
• 溶解度: Dichloromethane
• 溶解度: DMF
• 溶解度: DMSO
• 溶解度: Ether
• 溶解度: Ethyl Acetate
• 溶解度: Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

A Simvastatin intermediate; Lovastatin analog has the activities of decreasing blood cholesterol and low-d. lipoprotein, can be used to preparation hypolipidemic medicine.

参考文献

• Endo, A., et al.: J. Antibiot., 39, 1609 (1986)
• Aniya, Y., et al.: Gen. Pharmacol., 32, 225 (1986)
• Li, Y., et al.: J. Pharm. Biomed. Anal., 35, 1101 (1986)
• Akihisa, T., et al.: Chem. Biodivers, 2, 1305 (1986)