3α-Hydroxydesoxy Artemether

• 产品号: H939050
• CAS号: 174097-70-2
• 分子式: C16H26O5
• 分子量: 298.37464

产品别名

• 标题: 3α-Hydroxydesoxy Artemether
• IUPAC标准名: (1S,2R,4S,5R,8S,9R,10R,12S,13R)-10-methoxy-1,5,9-trimethyl-11,14,15-trioxatetracyclo[10.2.1.0^4,^1^3.0^8,^1^3]pentadecan-2-ol
• IUPAC传统名: (1S,2R,4S,5R,8S,9R,10R,12S,13R)-10-methoxy-1,5,9-trimethyl-11,14,15-trioxatetracyclo[10.2.1.0^4,^1^3.0^8,^1^3]pentadecan-2-ol
• 别名: [2S-(2α,3α,3aβ,6β,6aβ,8β,9β,10aα,10bβ)]-Decahydro-2-methoxy-3,6,9-trimethyl-10aH-9,10b-Epoxypyrano[4,3,2-jk][2]benzoxepin-8-ol; 3α-Hydroxydeoxyartemether; (2S,3R,3aS,6R,6aS,8R,9S,10aR,10bR)-Decahydro-2-methoxy-3,6,9-trimethyl-10aH-9,10b-epoxypyrano[4,3,2-jk][2]benzoxepin-8-ol

产品登记号

• CAS号: 174097-70-2

产品详细信息

详细说明 (English)

A metabolite of Artemether (A777400) and derivative of the antimalarial drug Artemisinin (A777500). Studies suggest that it may display neurotoxicity in animals due to its interaction with iron.

参考文献

• Smith, S.L. et al.: Neurotoxicology, 19, 557 (1998)
• Abourashed, E.A. et al.: J. Natur. Prod., 59, 251 (1998)