Hydroxy Bosentan-d6

• 产品号: H830273
• CAS号: 1246817-57-1
• 分子式: C27H29N5O7S
• 分子量: 567.61346

产品别名

• 标题: Hydroxy Bosentan-d6
• IUPAC标准名: 4-[1-hydroxy-2-(^2H₃)methyl(3,3,3-^2H₃)propan-2-yl]-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]benzene-1-sulfonamide
• IUPAC传统名: 4-[1-hydroxy-2-(^2H₃)methyl(3,3,3-^2H₃)propan-2-yl]-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]benzenesulfonamide
• 别名: Ro 48-8634-d6; Ro 48-5033-d6; 4-[2-Hydroxy-1,1-(dimethyl-d6)ethyl]-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide

产品登记号

• CAS号: 1246817-57-1

产品详细信息

详细说明 (English)

A labelled analogue of the active metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator.

参考文献

• Clozel, M., et al.: J. Pharmacol. Exp. Ther., 270, 228 (1994)
• Gutsch, G., et al.: Cardiovasc. Drugs Ther., 10, 717 (1994)
• Weber, C., et al.: Clin Pharmacol. Ther., 60, 124 (1994)
• Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998)