rac cis-3-Hydroxy Apatinib 3-O-β-D-Glucuronide

• 产品号: H802110
• CAS号: 1376331-61-1
• 分子式: C30H31N5O8
• 分子量: 589.59584

产品别名

• 标题: rac cis-3-Hydroxy Apatinib 3-O-β-D-Glucuronide
• IUPAC标准名: (2S,3S,4S,5R,6R)-6-{[(1R)-3-cyano-3-(4-{2-[(pyridin-4-ylmethyl)amino]pyridine-3-amido}phenyl)cyclopentyl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC传统名: (2S,3S,4S,5R,6R)-6-{[(1R)-3-cyano-3-(4-{2-[(pyridin-4-ylmethyl)amino]pyridine-3-amido}phenyl)cyclopentyl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• 别名: cis-3-Hydroxyapatinib β-O-Glucuronide; rel-(1R,3R)]-3-Cyano-3-[4-[[[2-[(4-pyridinylmethyl)amino]-3-pyridinyl]carbonyl]amino]phenyl]cyclopentyl β-D-Glucopyranosiduronic Acid

产品登记号

• CAS号: 1376331-61-1

产品详细信息

详细说明 (English)

cis-3-Hydroxy Apatinib 3-O-β-D-Glucuronide is a glucuronide conjugate of cis-3-Hydroxy Apatinib and a metabolite of the antiangiogenic agent and selective VEGFR2 inhibitor Apatinib (A726150).

参考文献

• Ding, J, et al.: J. Chrom B Anal. Technol. Biomed. Life Sci., 895, 108 (2012)