(2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester

• 产品号: H656565
• CAS号: 102195-79-9
• 分子式: C11H19NO5
• 分子量: 245.27226

产品别名

• 标题: (2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester
• IUPAC标准名: 1-tert-butyl 2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate
• IUPAC传统名: 1-tert-butyl 2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate
• 别名: Methyl (4S)-N-Boc-4-hydroxy-L-prolinate; Methyl (2S,4S)-1-tert-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylate; (2S,4S)-4-Hydroxy-1,2-pyrrolidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester; (2S-cis)-4-Hydroxy-1,2-pyrrolidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester

产品登记号

• CAS号: 102195-79-9

产品详细信息

详细说明 (English)

2S,4S)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.

参考文献

• Freer, R., et al.: Biochemistry, 21, 257 (1982)
• Higgins, J., et al.: J. Med. Chem., 39, 1013 (1982)
• Cavicchioni, G., et al.; Bioorg. Chem., 34, 298 (1982)
• Selvatici, R., et al.: Eur. J. Pharmacol., 534, 1 (1982)