2-(2-Heptynylthio)phenol Acetate

• 产品号: H288500
• CAS号: 209125-28-0
• 分子式: C15H18O2S
• 分子量: 262.36722

产品别名

• 标题: 2-(2-Heptynylthio)phenol Acetate
• IUPAC标准名: 2-(hept-2-yn-1-ylsulfanyl)phenyl acetate
• IUPAC传统名: 2-(hept-2-yn-1-ylsulfanyl)phenyl acetate
• 别名: APHS

产品登记号

• CAS号: 209125-28-0

产品详细信息

详细说明 (English)

An O-acetyl, S-alkyl thio ether of 2-thio phenol. It is a potent inhibitor of both COX-1 and COX-2, with IC50 values of 17 and 0.8uM for human recombinant COX-1 and COX-2 respectively. APHS exhibits 20-fold selectivity toward the inhibition of COX-2, ye

参考文献

• Kalgutkar, A.S., et a.: Science, 280, 1268 (1998)