Genistein-2',3',5',6'-d4 (Major)

• 产品号: G350010
• CAS号: 187960-08-3
• 分子式: C15H10O5
• 分子量: 270.2369
• 保 存: -20°C Freezer

产品别名

• 标题: Genistein-2',3',5',6'-d4 (Major)
• IUPAC标准名: 5,7-dihydroxy-3-[4-hydroxy(^2H₄)phenyl]-4H-chromen-4-one
• IUPAC传统名: 5,7-dihydroxy-3-[4-hydroxy(^2H₄)phenyl]chromen-4-one
• 别名: Baichanin A-d4; Bonistein-d4; GeniVida-d4; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d4; 4',5,7-Trihydroxyisoflavone-d4; Genisteol-d4; NSC 36586-d4; Prunetol-d4; Sophoricol-d4

产品登记号

• CAS号: 187960-08-3

产品性质

• 外观: Yellow Solid
• 熔点: 290-292°C (dec.)
• 溶解度: DMSO
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell prolif

参考文献

• Akiyama, T., et al.: J. Biol. Chem., 262, 5592 (1987)
• O'Dell, T.J., et al.: Nature, 353, 588 (1987)
• Aharonovits, O., et al.: Biochim Biophys. Acta, 1112, 181 (1987)
• Platanias, L.C., et al.: J. Biol. Chem., 267, 24053 (1987)
• Yoshida, H., et al.: Biochi