Genistein-4,6,2',3',5',6'-d6Discontinued See G350010

• 产品号: G350002
• 分子式: C15H10O5
• 分子量: 270.2369

产品别名

• 标题: Genistein-4,6,2',3',5',6'-d6Discontinued See G350010
• IUPAC标准名: 5,7-dihydroxy-3-[4-hydroxy(^2H₄)phenyl](6,8-^2H₂)-4H-chromen-4-one
• IUPAC传统名: 5,7-dihydroxy-3-[4-hydroxy(^2H₄)phenyl](6,8-^2H₂)chromen-4-one
• 别名: 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d6; Genisteol-d6; NSC 36586-d6; 4',5,7-Trihydroxyisoflavone-d6; GeniVida-d6; Baichanin A-d6; Bonistein-d6; Prunetol-d6; Sophoricol-d6

产品性质

• 外观: Light Yellow Solid

产品详细信息

详细说明 (English)

Labelled Genistein (G350000). Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of AT

参考文献

• Akiyama, T., et al.: J. Biol. Chem., 262, 5592 (1987)
• O'Dell, T.J., et al.: Nature, 353, 588 (1987)
• Aharonovits, O., et al.: Biochim Biophys. Acta, 1112, 181 (1987)
• Platanias, L.C., et al.: J. Biol. Chem., 267, 24053 (1987)
• Yoshida, H., et al.: Biochi