rac Frovatriptan-d3 Succinate Monohydrate

• 产品号: F768502
• 分子式: C18H25N3O6
• 分子量: 379.4076
• 保 存: -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: rac Frovatriptan-d3 Succinate Monohydrate
• IUPAC标准名: 3-[(^2H₃)methylamino]-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide butanedioic acid hydrate
• IUPAC传统名: 6-[(^2H₃)methylamino]-6,7,8,9-tetrahydro-5H-carbazole-3-carboxamide succinic acid hydrate
• 别名: Migard-d3; Frova-d3; Frovelan-d3; Miguard-d3; rac-2,3,4,9-Tetrahydro-3-(methyl-d3-amino)-1H-carbazole-6-carboxamide Butanedioic Acid Monohydrate

产品性质

• 外观: Off-White Solid
• 熔点: 211-214°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

Serotonin 5-HT1B/1D receptor agonist. It is a triptan drug for the treatment of migraine headaches. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.

参考文献

• Siow, C.H., et al.: Cephalalgia, 24, 1045 (1997)
• Poolsup, N., et al.: J. Clin. Pharm. Ther., 30, 521 (1997)
• Parsons, A.A., et al.: J. Cardiovasc. Pharmacol., 30, 136 (1997)