N-Formyl Leurosine (Vincristine Impurity G)

• 产品号: F700650
• CAS号: 54022-49-0
• 分子式: C46H54N4O10
• 分子量: 822.94176
• 保 存: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: N-Formyl Leurosine (Vincristine Impurity G)
• IUPAC标准名: methyl (13S,15R,16R,18S)-13-[(1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-8-formyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2(7),3,5,13-tetraen-4-yl]-18-ethyl-17-oxa-1,11-diazapentacyclo[13.4.1.0^4,^1^2.0^5,^1^0.0^1^6,^1^8]icosa-4(12),5,7,9-tetraene-13-carboxylate
• IUPAC传统名: methyl (1S,13S,15R,16R,18S)-13-[(1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-8-formyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8,16-diazapentacyclo[10.6.1.0^1,^9.0^2,^7.0^1^6,^1^9]nonadeca-2(7),3,5,13-tetraen-4-yl]-18-ethyl-17-oxa-1,11-diazapentacyclo[13.4.1.0^4,^1^2.0^5,^1^0.0^1^6,^1^8]icosa-4(12),5,7,9-tetraene-13-carboxylate
• 别名: N-Formyl N-demethylleurosine; NSC 269419; Leuroformine; N-Demethyl-N-formylleurosine; (3'α,4'α)-4'-Deoxy-3',4'-epoxy-22-oxovincaleukoblastine; 22-Oxoleurosine; F-Leurosine; Formylleurosine; Vinformide; Vincristine Impurity G

产品登记号

• CAS号: 54022-49-0

产品性质

• 外观: Off-White Solid
• 熔点: 200-210°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

Degradation products of Vincristine. A Vinca dimer, a potent cytostatic agent. Vincristine Impurity G.

参考文献

• Erdelyi-Toth, V., et al.: Eur. J. Cancer, 17, 329 (1981)
• Ronai-Lukacs S; Eur. J. Drug Metab. Pharmacokinet., 7, 4 (1981)