Flutax 1

• 产品号: F599400
• CAS号: 191930-58-2
• 分子式: C71H66N2O21
• 分子量: 1283.28454

产品别名

• 标题: Flutax 1
• IUPAC标准名: 5-{[(2S)-1-{[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-2-(benzoyloxy)-1-hydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-9-yl]oxy}-1-oxopropan-2-yl]carbamoyl}-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
• IUPAC传统名: 5-{[(2S)-1-{[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-2-(benzoyloxy)-1-hydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-9-yl]oxy}-1-oxopropan-2-yl]carbamoyl}-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid
• 别名: 7-O-[N-(4’-Fluoresceincarbonyl)-L-alanyl] Taxol; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-9-[(2R,3S)-3-(benzoylamino)-2-hydroxy-1-oxo-3-phenylpropoxy]-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-4-yl Ester N-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)carbonyl]-L-alanine

产品登记号

• CAS号: 191930-58-2

产品性质

• 外观: Orange Solid
• 溶解度: DMSO
• 溶解度: Ethanol

产品详细信息

详细说明 (English)

Flutax 1 is a fluorescent taxol derivative that binds to the taxol microtubule binding site with high affinity (Ka ~ 107M-1). Flutax 1 is useful for direct imaging of the microtubule cytoskeleton. Excitation maximum ~ 495 nm; emission maximum ~ 520 nm.

参考文献

• Evangelio, J.A., et al.: Cell Motil., Cytoskeleton, 39, 73 (1995)
• Souto, A.A., et al.: Angew. Chem. Int. Ed. Engl., 34, 2710 (1995)
• Abal., M., et al.: Cell Motil. Cytoskeleton, 49, 1 (1995)
• Diaz, J.F., et al.: J. Biol. Chem., 275, 26265, 2001,