N-[4-[1-(2-Fluorobenzyl)-3-butyl-2,6-dixo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]phenyl]acetamide

• 产品号: F588520
• CAS号: 628279-07-2
• 分子式: C25H26FN5O3
• 分子量: 463.5040432

产品别名

• 标题: N-[4-[1-(2-Fluorobenzyl)-3-butyl-2,6-dixo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]phenyl]acetamide
• IUPAC标准名: N-[4-({3-butyl-1-[(2-fluorophenyl)methyl]-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl}methyl)phenyl]acetamide
• IUPAC传统名: N-[4-({3-butyl-1-[(2-fluorophenyl)methyl]-2,6-dioxo-7H-purin-8-yl}methyl)phenyl]acetamide
• 别名: N-[4-[[3-Butyl-1-[(2-fluorophenyl)methyl]-2,3,6,9-tetrahydro-2,6-dioxo-1H-purin-8-yl]methyl]phenyl]acetamide

产品登记号

• CAS号: 628279-07-2

产品详细信息

详细说明 (English)

It is used for the preparation of amide-substituted xanthine derivatives as phosphoenolpyruvate carboxykinase inhibitors with gluconeogenesis modulating activity for treating type 2 diabetes.

参考文献

• Kawashima, Y., et al.: Chem. Pharm. Bull., 43, 1132 (1995)
• Sun, Y., et al.: J. Biol. Chem., 277, 23301 (1995)
• Foley, L., et al.: Bioorg. Med. Chem. Lett., 13, 3871 (1995)